KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHA4
All Species:
27.27
Human Site:
S574
Identified Species:
66.67
UniProt:
P54764
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54764
NP_004429.1
986
109860
S574
F
V
I
S
R
R
R
S
K
Y
S
K
A
K
Q
Chimpanzee
Pan troglodytes
P0C0K6
1020
110674
R620
V
L
A
V
V
F
Q
R
K
R
R
G
T
G
Y
Rhesus Macaque
Macaca mulatta
XP_001106493
986
109814
S574
F
V
I
S
R
R
R
S
K
Y
S
K
A
K
Q
Dog
Lupus familis
XP_536084
1027
113994
S615
F
V
I
S
R
R
R
S
K
Y
S
K
A
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q03137
986
109783
S574
F
V
I
S
R
R
R
S
K
Y
S
K
A
K
Q
Rat
Rattus norvegicus
P54759
998
111935
F576
L
V
F
M
V
F
G
F
I
I
G
R
R
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506050
986
110059
S574
F
V
I
S
R
R
R
S
K
Y
S
K
A
K
Q
Chicken
Gallus gallus
Q07496
986
109464
S574
F
V
I
S
R
R
R
S
K
Y
S
K
A
K
Q
Frog
Xenopus laevis
Q91845
986
109822
S573
F
V
I
S
R
R
R
S
K
Y
S
K
A
K
Q
Zebra Danio
Brachydanio rerio
O13146
981
109636
C572
F
I
V
S
G
R
R
C
G
Y
I
K
A
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.8
99.9
93.3
N.A.
98.4
62.2
N.A.
96.1
94.2
88.9
64.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.3
100
94.5
N.A.
99.4
78
N.A.
98.2
97.3
94.8
79.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
100
100
100
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
100
100
100
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
80
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
80
0
10
0
0
20
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
10
0
10
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
70
0
0
0
0
0
10
10
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
80
0
0
80
0
80
0
% K
% Leu:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
80
% Q
% Arg:
0
0
0
0
70
80
80
10
0
10
10
10
10
0
0
% R
% Ser:
0
0
0
80
0
0
0
70
0
0
70
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
10
80
10
10
20
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _